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Dr. Igor Grant, M.D., F.R.C.P.(C)
Dr. Grant is Distinguished Professor of Psychiatry and director of HIV Neurobehavioral Research Programs at the University of California San Diego. Dr. Grant is a neuropsychiatrist who graduated from the University of British Columbia School of Medicine, and received specialty training in psychiatry at the University of Pennsylvania, and additional training in neurology at the Institute of Neurology (Queen Square) London, U.K. Dr. Grant’s academic interests focus on the effects of various diseases on brain and behavior, with an emphasis on translational studies in HIV, and drugs of abuse. He has contributed to approximately 500 scholarly publications and is principal investigator of several NIH studies, including a NIDA P50 (Translational Methamphetamine AIDS Research Center – TMARC) and NIMH funded HIV Neurobehavioral Research Center (HNRC), California NeuroAIDS Tissue Network (CNTN), and CNS HIV AntiRetroviral Therapy Effects Research (CHARTER).
"Neuropsychiatric Manifestations of HIV"
HIV Associated Neurocognitive Disorders (HAND) persist despite advent of modern combination antiretroviral therapies (CART). Indeed, the rates of neurocognitive impairment have not changed greatly over the past 25 years, with the exception of markedly reduced incidence of severe forms of HIV dementia. Those that are least likely to develop HAND include individuals who have never had severe immuno-compromise and are currently well controlled on CART. Persistence of HAND may be related to additional factors that may contribute to neurocognitive impairment, including substance abuse, coinfection with hepatitis C, and other comorbidities, which themselves might predict worse outcome in the context of HIV. Comorbid psychiatric disorders, such as bipolar disorder may also contribute through lessened adherence to CART. Treatment with more highly CNS penetrating ARV may have some neurocognitive benefits, but reduction of rates of HAND may depend on very early interventions that prevent CNS complications starting immediately after a person becomes infected. |
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Dr. Anthony Bailey,
University of British Columbia
"Autism: The next 10 years"
Dr Anthony Bailey became Professor and Chair of Child and Adolescent Psychiatry at UBC in July 2010. He took a BSc in Experimental Pathology at the London Hospital Medical College, where he subsequently graduated in Medicine in 1982. After a year of Paediatrics he trained as a Child Psychiatrist at the Bethlem Royal and Maudsley Hospitals and Institute of Psychiatry (IoP) in London. Following an MRC Training Fellowship he became an MRC Clinical Scientist and Head of the Autism Section at The MRC Child Psychiatry Unit at the IoP, subsequently the MRC Social, Genetic and Developmental Psychiatry Research Centre. In 2002 Dr Bailey was appointed to the Cheryl and Reece Scott Chair of Psychiatry at the University of Oxford: the first medical chair devoted to the study of autism.
Dr Bailey's research has investigated the neurobiological basis of autistic disorders, using genetic, neuropathological and neuroimaging approaches. Until his move to Canada, Dr Bailey coordinated the International Molecular Genetic Study of Autism Consortium: a large international team of clinicians and scientists brought together in 1995 to identify susceptibility genes for autism; this group published the first complete genome scan of autism and has been at the forefront of the UK’s contribution to understanding the genetic basis of autism. At Oxford Dr Bailey built the first Magnetoencephalographic Centre purpose designed for the study of autism and other neurodevelopmental disorders, which was opened by HRH The Princess Royal in 2007. Dr Bailey's clinical work focuses on teenagers and adults with Autism Spectrum Disorders and he has worked extensively in the developing world to assist in service development. Dr Bailey has been a Director of the Prior’s Court Foundation (a residential school for young people with autism), Research Autism (the UK Charity devoted to funding research into treatments for autism) and the Oxford Playhouse Theatre. At Oxford he was a Curator of Libraries and a member of the Committee for Museums and Scientific Collections as well as the Continuing Education Board. Dr Bailey has served as an Editor of the Journal of Neural Transmission and is the founding Editor-in-Chief of Autism Research: the Journal of the International Society of Autism Research.
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