Timothy H. Murphy

Dr. Tim Murphy is a foundational scientist who studies how the mouse cortex adapts after stroke by remapping of brain function from damaged to surviving areas. The Murphy Lab develops new imaging and optogenetic methods that have parallels to human brain imaging and stimulation tools. He leads UBC’s Dynamic Brain Circuits in Health and Disease Cluster and participates in the Canadian Neurophotonics Platform. Dr. Murphy is also a founding member of the Psychiatry AI Collaboration at UBC working group.

Dr. Murphy uses high-resolution imaging of individual synapses and sensorimotor circuits in live mice to provide insight into mechanisms of initial stroke damage and stroke recovery. The lab has developed models of neurological and psychiatric diseases through internet-enabled mouse homecages used to manipulate and assess brain activity. More recent work has focused on developing a synthetic human form as a means of quantifying changes in neurological disease.

Peer-reviewed publications

2010 UBC Killam Research Prize Science, Applied Science, Medicine Category

2025 inaugural AI and Health Network Fellows Awardee as Principal Investigator for the project An Explainable AI Framework for Collaborative Assessment of Motor Disorders using De-Identified 3D Biomarkers